| 产品详情 |
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| Product Name | PF-573228 |
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| Description | Purity >98% by HPLC. PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC50 of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone |
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| Gene, Accession, CAS # | CAS: 869288-64-2 |
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| Catalog # | LS-H3365 |
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| Order / More Info | PF-573228 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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