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| Product Name | PPP1R15A, Recombinant, Human, aa40-674, His-Tag (Protein Phosphatase 1 Regulatory Subunit 15A) |
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| Description | Purity ~90% (SDS-PAGE). Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. Source: Recombinant protein corresponding to aa40-674 from human PPP1R15A, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~71.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Growth arrest and DNA damage-inducible protein, GADD34, Myeloid differentiation primary response protein MyD116 homolog |
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| Gene, Accession, CAS # | SwissProt: O75807 |
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| Catalog # | 374821 |
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| Order / More Info | PPP1R15A, Recombinant, Human, aa40-674, His-Tag (Protein Phosphatase 1 Regulatory Subunit 15A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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