产品名称 NOSIP, Control Peptide (eNOS interacting protein) from UNITED STATES BIOLOGICAL
产品货号 N5355-01
产品价格 现货询价,电话:010-67529703
产品规格 1mg
产品品牌 UNITED STATES BIOLOGICAL
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Product NameNOSIP, Control Peptide (eNOS interacting protein)
DescriptionPurity > 90% by HPLC. Synthetic peptide (Ac-CAEKSRPVMQA-NH2) (linear) corresponding to aa292-301 of human NOSIP with a N-terminal cysteine for conjugation. The peptide has an acetyl group blocking the amino terminus and an amide group blocking the carboxyl terminus. Production of nitric oxide (NO) in endothelial cells is regulated by direct interactions of endothelial nitric oxide synthase (eNOS) with effector proteins such as Ca2+-calmodulin, by posttranslational modifications such as phosphorylation via protein kinase B, and by translocation of the enzyme from the plasma membrane caveolae to intracellular compartments. Reversible acylation of eNOS is thought to contribute to the intracellular trafficking of the enzyme; however, protein factor(s) that govern the translocation of the enzyme are still unknown. Here we have used the yeast two-hybrid system and identified a novel 34kD protein, termed NOSIP (eNOS interacting protein), which avidly binds to the carboxyl-terminal region of t
Size1mg
Concentrationn/a
ApplicationsWB
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Catalog #N5355-01
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