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| Product Name | Myosin Light Chain 2, Non-muscle, Recombinant, Human |
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| Description | Purity ~90% by SDS-PAGE. Non muscle Myosins are required for cytokinesis at the end of cell division, when a contractile ring near the plasmalemma divides the cytoplasm of the daughter cells. They are involved in cytoplasmic streaming movements in tissues, and especially in activation of motile cells such as fibroblasts and macrophages. Activation of non-muscle myosin-II is achieved by phosphorylation of Ser33 in the motif KKRPQRATSN by a dedicated, Ca+2 Calmodulin regulated light chain kinase (MLCK). Activity: Assayed for phosphorylation by MLCK. Applications: Suitable for use in ELISA, Western Blot and Inhibition Assays. Other applications have not been tested. Amino Acid Sequence: MSSKKAKTKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDAYL DAMMNEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEATGTIQE DYLRELLTTM GDRFTDEEVD ELYREAPIDK KGNFNYIEFT RILKHGAKDK DD |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Myosin Light Chain 2, Non-muscle, Recombinant, Human (MLC2, Myosin Regulatory Light Chain, MRLC, RLC, LC20) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M9850-09N |
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| Order / More Info | Myosin Light Chain 2, Non-muscle, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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