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| Product Name | LYN, 1-512aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 61.0 kDa (535aa). Purity >90% by SDS-PAGE. Tyrosine-protein kinase Lyn, also known as LYN, is a member of the src family of non-receptor protein tyrosine kinases that is predominantly expressed in haematopoietic tissues. This protein is Involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. It Induces SAPK by a MKK7- and MEKK1-dependent mechanism. The LYN -> MEKK1 -> MKK7 -> SAPK pathway is functional in the induction of apo |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Tyrosine-protein kinase Lyn; JTK8; p53Lyn; p56Lyn] |
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| Gene, Accession, CAS # | LYN, Gene ID: 4067, Accession: NP_002341 |
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| Catalog # | MBS205205 |
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| Order / More Info | LYN, 1-512aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Gaul B.S., et al. (2001) J. Biol. Chem. Res. 275:16174-16182; Rena G., et al. (2001) Mol. Pharmacol. 59:996-1011 |
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