产品详情 |
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Antigenic Specificity | CEACAM1/5 |
Clone | 4/3/17 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | flow cytometry, CELISA, ELISA, Western blots and immunohistology on cryosections |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
Immunogen | cDNA |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | GM-0511 |
Price | |
Order / More Info | CEACAM1/5 Antibody from ALDEVRON FREIBURG GmbH |
Product Specific References | n/a |
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