| 产品详情 |
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| Antigenic Specificity | TATA binding protein TBP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for TATA-box-binding protein(TBP) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. |
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| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human TBP(227-246aa EEQSRLAARKYARVVQKLGF), identical to the related rat and mouse sequences. |
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| Other Names | TATA-box-binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;Transcription initiation factor TFIID TBP subunit;TBP;GTF2D1, TF2D, TFIID; |
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| Gene, Accession # | TBP, UniProt: P20226 |
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| Catalog # | PA1534 |
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| Price | |
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| Order / More Info | TATA binding protein TBP Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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