| 产品详情 |
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| Product Name | BML-277 |
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| Description | MW: 363.8. Purity >98% (TLC; 1:1 ethylacetate: hexane; Rf=0.17); NMR (Conforms). CHK2 inhibitorScientific Background: A highly selective inhibitor of Chk2 (IC50=15 nM). Displays <25% inhibition of 35 other kinases at 10 uM) (1). It possesses potent radioprotective activity and prevents apoptosis of human T-cells subjected to ionizing radiation (EC50= 3-7.6 uM) (1). It is a useful tool for determining the role of Chk2 in cellular signaling (2). |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [K252B] |
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| Gene, Accession, CAS # | CAS: 516480-79-8 |
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| Catalog # | MBS515042 |
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| Order / More Info | BML-277 from MYBIOSOURCE INC. |
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| Product Specific References | 1. K L Arienti et al. J. Med. Chem. 2005 48:1873 2. Y Pereg et al. Mol. Cell. Biol. 2006 26:6819 |
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