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| Product Name | HPD, 1-393aa, Human, His tag, E Coli |
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| Description | MW: 47 kDa (413aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. 4-hydroxyphenylpyruvate dioxygenase isoform 1, also known as HPD, is an Fe-containing enzyme, that catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Existing as a homodimer, HPD uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding HPD are the cause of tyrosinemia |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [4-hydroxyphenylpyruvate dioxygenase isoform 1; 4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD] |
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| Gene, Accession, CAS # | HPD, Gene ID: 3242, Accession: NP_002141 |
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| Catalog # | MBS203885 |
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| Order / More Info | HPD, 1-393aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Wada GH., et al. (1975) J Biol Chem J. 250 (17):6720-6.; uetschi u., et al. (1997) Genomics. 44:292-299. |
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