| 产品详情 |
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| Product Name | Recombinant Mouse Protein CBFA2T2 (Cbfa2t2) |
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| Description | 1-594aa, Full length protein. MW: 63,921 Da. Purity >85% (SDS-PAGE). In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5 -region of the RUNX1 (AML1) gene fused to the 3 -region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressorhistone deacetylase complex to block hematopoietic differentiati |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Baculovirus), 0.2 mg (E-Coli), 0.05 mg (Mammalian-Cell), 0.2 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [protein CBFA2T2 isoform 2; Protein CBFA2T2; protein CBFA2T2; core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human); MTG8-like protein; MTG8-related protein 1] |
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| Gene, Accession, CAS # | Cbfa2t2, Gene ID: 12396, Accession: NP_033953.1 |
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| Catalog # | MBS1008801 |
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| Price | |
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| Order / More Info | Recombinant Mouse Protein CBFA2T2 (Cbfa2t2) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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