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Product Name | ADAM10, 214-672aa, Human, His-tag, Baculovirus |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. ADAM10, as known as disintegrin and metalloproteinase domain-containing protein 10 isoform 1, is a member of the ADAM family that contains a disintegrin and metallogrotease-like domain. This protein is a sheddase, and has a broad specificity for peptide hydrolysis reactions. Also, it cleaves ephrin, within the ephrin/eph complex, formed between two cell surfaces. When ephrin is freed from the opposing cell, the entire ephrin/eph complex is endocytosed. In neurons, ADAM10 is the most important enzyme with alpha-secretase activity for proteolytic processing of the amyloid precursor protein. Recombinant human ADAM10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Disintegrin and metalloproteinase domain-containing protein 10 isoform 1 , ADAM10, AD10, AD18, CD156c, HsT18717, kuz, MADM, RAK |
Gene, Accession, CAS # | NP 001101 |
Catalog # | ATGP3448 |
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Order / More Info | ADAM10, 214-672aa, Human, His-tag, Baculovirus from ATGen |
Product Specific References | n/a |
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