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| Product Name | APOBEC3A, Recombinant, Human, aa1-199, His-SUMO-Tag (Probable DNA dC->dU-editing Enzyme APOBEC-3A) |
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| Description | Purity ~90% (SDS-PAGE). DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Source: Recombinant protein corresponding to aa1-199 from human APOBEC3A, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~39kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Phorbolin-1 |
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| Gene, Accession, CAS # | SwissProt: P31941 |
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| Catalog # | 372296 |
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| Order / More Info | APOBEC3A, Recombinant, Human, aa1-199, His-SUMO-Tag (Probable DNA dC->dU-editing Enzyme APOBEC-3A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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