| 产品详情 |
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| Product Name | Recombinant Human DNA mismatch repair protein Msh6 |
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| Description | 1-400aa; Partial. MW: 60.03kD. Purity >90% as determined by SDS-PAGE. Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heter |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160] |
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| Gene, Accession, CAS # | MSH6, Gene ID: 2956, Accession: NP_000170.1 |
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| Catalog # | MBS957892 |
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| Order / More Info | Recombinant Human DNA mismatch repair protein Msh6 from MYBIOSOURCE INC. |
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| Product Specific References | hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.Acharya S., Wilson T., Gradia S., Kane M.F., Guerrette S., Marsischky G.T., Kolodner R.D., Fishel R.Proc. Natl. Acad. Sci. U.S.A. 93:13629-13634(1996) Alternative splicing of GTBP in normal human tissues.Shiwaku H.O., Wakatsuki S., Mori Y., Fukushige S., Horii A.DNA Res. 4:359-362(1997) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wak |
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