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Product Name | ABT-737 |
Description | A small-molecule inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w. In vitro, ABT-737 binds Bcl-xL, Bcl-2 and Bcl-w with comparable high affinity, while it has over 1000-fold lower affinities for Bcl-B, Bfl-1 and Mcl-1. Displays wide range of single-agent activity against acute lymphoblastic leukemia (ALL) cell lines and xenografts. MW: 813.43. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
Gene, Accession, CAS # | CAS: 852808-04-9 |
Catalog # | 2463-5 |
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Order / More Info | ABT-737 from BIOVISION, INC. |
Product Specific References | n/a |
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