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| Product Name | PIP5K1C, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PIP5K1C or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with beta-catenin and increases beta-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance beta-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitating RhoA GTPase and integrin activation by chemoattractants. Source: Recombinant protein corresponding to human PIP5K1C, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~120kD Specific Activity: 220nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PIP5K1C, Recombinant, Human, GST-Tag (Phosphatidylinositol-4-Phosphate 5-Kinase Type-1 Gamma, KIAA0589, LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4) |
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| Gene, Accession, CAS # | Accession: NM_012398 |
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| Catalog # | 500380 |
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| Order / More Info | PIP5K1C, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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