| 产品详情 |
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| Antigenic Specificity | ABCE1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: bovine, canine, chicken, hamster, horse, monkey, rabbit) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis. |
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| Immunogen | E. coli-derived human ABCE1 recombinant protein (Position: K419-D599). Human ABCE1 shares 100% amino acid (aa) sequence identity with mouse ABCE1. |
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| Other Names | ATP-binding cassette sub-family E member 1;2'-5'-oligoadenylate-binding protein;HuHP68;RNase L inhibitor;Ribonuclease 4 inhibitor;RNS4I;ABCE1;RLI, RNASEL1, RNASELI, RNS4I;OK/SW-cl.40; |
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| Gene, Accession # | ABCE1, UniProt: P61221 |
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| Catalog # | PB10020 |
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| Price | |
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| Order / More Info | ABCE1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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