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| Product Name | GJA1, Recombinant, Human, aa233-382, His-Tag (Gap Junction alpha-1 Protein) |
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| Description | Purity ~90% (SDS-PAGE). Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity). Source: Recombinant protein corresponding to aa233-382 from human Gap Junction alpha-1 Protein, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~20.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Connexin-43, Cx43 Gap junction 43kD heart protein |
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| Gene, Accession, CAS # | SwissProt: P17302 |
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| Catalog # | 373437 |
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| Order / More Info | GJA1, Recombinant, Human, aa233-382, His-Tag (Gap Junction alpha-1 Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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