产品详情 |
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Product Name | A-769662 |
Description | A small molecule thienopyridone that activates AMPK directly in cell-free assays (EC50 = 116 nM) and intact cells by allosterically activating AMPK and inhibiting its dephosphorylation on Thr172 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | obesity syndromes kinases diabetes atherosclerosis AMP-activated proteins kinases AMPK lipids metabolisms glucose metabolic stress activators activates active glucose uptakes diseases A769662 A-769662 A 769662 A769,662 A 769,662 A-792,662 thienopyridone inhibits inhibiting inhibitions inhibitors CYP450 fatty acids oxidations adipocytes differentiations uptake up-take alpha .alpha. a beta .beta. b gamma .gamma. g heterotrimers sensors regulates regulating cells cellular energy homeostasis small molecules thienopyridones cell-free assays intact allosterically Thr172 stimulates CYP450-mediated cytochromes P450 dephosphorylations skeletal muscles endothelium endothelial |
Gene, Accession, CAS # | CAS: 844499-71-4 |
Catalog # | 11900-10 |
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Order / More Info | A-769662 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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