产品详情 |
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Product Name | A-771726 |
Description | Reversibly inhibits dihyroorotate dehydrogenase, the rate-limiting step in the de novo synthesis of pyrimidines, preventing DNA synthesis of activated lymphocytes (IC50s = 0.09, 3.5, and 12.5 µM for rat, mouse, and human, respectively); also inhibits tyrosine kinases responsible for early T cell and B cell cycling and the production of PGE2, MMP-1, and IL-6 in immune-activated synoviocytes |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Flucyamide|HMR 1726|SU 20|Teriflunomide |
Gene, Accession, CAS # | CAS: 163451-81-8 |
Catalog # | 14404-10 |
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Order / More Info | A-771726 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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