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| Product Name | Topoisomerase II (DNA) beta, Human, Western Blot Positive Control |
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| Description | Purity ≥ 90%. The topology of the DNA is a crucial issue in different biological processes like recombination, replication, transcription, and chromatin remolding. DNA topoisomerases are enzymes that control the amount of supercoiling in DNA. Without topoisomeras, DNA cannot replicate normally. The protein family of DNA topoisomerases is divided into two types (type I and II) based on their mechanism and physical properties. While the type I topoisomerases are monomeric and do not require ATP, the type II contain multi-subunits and depend on ATP for their activity. The type I enzymes include eukaryotic and bacterial topoisomerase I and III. The type II enzymes include bacterial DNA gyrase and topoisomerase IV and the eukaryotic topoisomerase II. Type I enzymes introduce transient single strand breaks in DNA, while type II enzymes produce transient double strand breaks in the DNA. Topo II plays important roles in synthesis and transcription of DNA as well as chromosomal segregation duri |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8065-23A |
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| Order / More Info | Topoisomerase II (DNA) beta, Human, Western Blot Positive Control from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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