| 产品详情 |
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| Product Name | Fumagillin (Amebacilin, Fugilin, Fumidil, Fumadil B, NSC9168, U5762) |
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| Description | Purity ~98% (H-NMR, MS). Meroterpenoid antibiotic. Anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Suppresses the HIV-1 infection of human macrophages through the inhibition of HIV-1 viral protein R (Vpr) activity. Inhibits neovascularization and might be useful in non-tumor diseases such as diabetic retinopathy, arthritis and psoriasis, which involve neovascularisation processes. Reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis. Source: Aspergillus fumigatus (Strain WDMH-35) Formula: C26H34O7 Solubility: Soluble in DMSO, acetone or chloroform. Slightly soluble in methanol or ethanol. Insoluble in H2O. Molecular Weight: ~458.6 |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207191 |
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| Order / More Info | Fumagillin (Amebacilin, Fugilin, Fumidil, Fumadil B, NSC9168, U5762) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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