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| Product Name | Fumarase, 44-510aa, Human, E Coli (Bioactivity Validated) |
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| Description | MW: 50.2kDa (467aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficienc |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Fumarate hydratase; FH; HLRCC; LRCC; MCL; MCuL1; Fumarate hydratase Fumarase; Fumarate hydratase mitochondrial; MCuL 1; Multiple hereditary cutaneous leiomyomata.] |
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| Gene, Accession, CAS # | FH; FH; MCL; FMRD; LRCC; HLRCC; MCUL1; Fumarase, Gene ID: 2271, Accession: NP_000134 |
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| Catalog # | MBS203208 |
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| Order / More Info | Fumarase, 44-510aa, Human, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Lehtonen R., et al. (2003) J. Med. Genet. 40 (3): e19.; Toro JR., et al. (2003) Am. J. Hum. Genet. 73 (1): 95-106.; |
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