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| Product Name | Fumarase Activity Colorimetric BioAssay™ Kit (Fumarate Hydratase, EC 4.2.1.2) |
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| Description | Fumarase (Fumarate Hydratase: EC 4.2.1.2) is an enzyme that catalyzes the reversible reaction of hydration and dehydration of fumarate to Malate. It has two forms: mitochondrial and cytosolic forms. The mitochondrial form of fumarase is one of the key enzymes in citric acid cycle, while cytosolic form is important for metabolism of amino acids and fumarate. In humans, fumarase deficiency leads to serious health problems such as fetal brain abnormality, hypotonia, and renal cell carcinoma. Therefore, accurate measurement of fumarase activity is important for preventing, diagnosis and mechanistic study of fumarase deficiency. Sample Type: Animal tissues: liver, heart, muscle etc. Cell culture: Adherent or suspension cells. Isolated mitochondria.? Intended Use: For use in the measurement of fumarase activity in various tissues/cells and analysis of citric acid cycle, reductive carboxylation cycle (CO2 fixation) and renal cell carcinomas. Sensitivity: This kit can detect <50U/ml of fumaras |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 219778 |
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| Order / More Info | Fumarase Activity Colorimetric BioAssay™ Kit (Fumarate Hydratase, EC 4.2.1.2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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