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| Product Name | Mammalian Degenerin 1, Rat (MDGE1, ASIC2, BNaC1) Control Peptide |
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| Description | Highly purified. Rat MDEG1 is 512 aa H+-gated cation channel protein. A 20aa Peptide sequence near the extracellular, N-terminus, of rat ASIC-b. Tissue acidosis that occurs in ischemia, tissue damage or inflammation is accompanied by pain. Proton-gated cation channels are activated by low pH in nociceptive neurons. H+-gated channels are members of the NaC/DEG superfamily that include: (1) Amiloride-sensitive epithelial Na+ channels (a, b, and g, and d-ENaC subunits); (2) A FMRFamide-gated channel (FaNaC), (3) and mechanosensory channel proteins of nematode degenerins (DEG). NaC/DEG superfamily is characterized by intracellular N and C-termini, two transmembrane domains, and a large extracellular loop. All members of this family are selective for Na+ and blocked by amiloride. The mammalian homolog of degenerins (MDEG or MDEG1; now designated ASIC for Acid Sensing Ion Channels). Three are at least three distinct proteins in ASIC family: ASIC1 (identical with human BNAC2 or BNC2), express |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A3793 |
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| Order / More Info | Mammalian Degenerin 1, Rat (MDGE1, ASIC2, BNaC1) Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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