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| Product Name | MOAP1, 1-351aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 41.9 kDa (374aa). Purity >85% by SDS-PAGE. Modulator of apoptosis 1, also known as MOAP1, belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. MOAP1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X (L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MOAP1 mediates apoptosis through a mechanism that involves binding to Bax. |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Modulator of apoptosis 1; MAP-1; PNMA4] |
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| Gene, Accession, CAS # | MOAP1, Gene ID: 64112, Accession: NP_071434 |
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| Catalog # | MBS205295 |
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| Order / More Info | MOAP1, 1-351aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Baksh S., et al. (2005) Mol Cell. 18:637-650.; Tan K O., et al. (2001) J Biol Chem. 276:2802-2807.; |
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