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| Product Name | BRAF, Recombinant, Human, aa432-766, His-Tag (Serine/Threonine-Protein Kinase B-Raf) |
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| Description | Purity ≥80% (SDS-PAGE). BRAF belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Recombinant protein corresponding to aa432-766 from human BRAF, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~40.6kD (360aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFSEDRN RMKTLGRRDS SDDWEIPDGQ ITVGQRIGSG SFGTVYKGKW HGDVAVKMLN VTAPTPQQLQ AFKNEVGVLR KTRHVNI |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_004324 |
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| Catalog # | 217979 |
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| Order / More Info | BRAF, Recombinant, Human, aa432-766, His-Tag (Serine/Threonine-Protein Kinase B-Raf) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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