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| Product Name | Human Insulin Like Growth Factor-I Recombinant |
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| Description | MW: 21,841 Da. Purity >95%, as determined by SDS-PAGE and HPLC. Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C- terminal propeptides (1). These isoforms are differentially expressed by various tissues (1). The 7.6 kDa mature IGF-I is identical between isoforms and is generated by proteolytic removal of the N- and C- term |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [igf-1; insulin like; igf1; igf-i] |
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| Gene, Accession, CAS # | IGF-I, Gene ID: 3479, Accession: NP_000609.1 |
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| Catalog # | MBS553053 |
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| Order / More Info | Human Insulin Like Growth Factor-I Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • statement by the growth hormone research society on the gh/IGF-I axis in extending health span .J Gerontol A Biol Sci Med Sci, Oct 2009; 64A: 1039 - 1044. • partial primary deficiency of insulin-like growth factor (igf) -i activity associated with igf1 mutation demonstrates its critical role in growth and brain development .J. Clin. Endocrinol. Metab., Sep 2009; 10.1210/jc.2009-0452. • myostatin inhibits IGF-I induced myotube hypertrophy through akt .Am J Physiol Cell Physiol, S |
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