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Product Name | Recombinant Human GM-CSF |
Description | Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. Like IL-3, GM-CSF is a multipotential growth factor, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. GM-CSF induces myeloid progenitor cells from bone marrow to form colonies containing macrophages and granulocytes in a semisolid medium. GM-CSF stimulates the development of neutrophils and macrophages and the proliferation and development of early erythroid, megakaryocytic and eosinophilic progenitor cells. GM-CSF, in combination with IL4 was demonstrated to induce in vitro generation of dendritic cells from monocytes (Caux C et al, Nature. 1992 Nov 19; 360 (6401):258-61). DDX-C-rhuGM-CSF is a bioactive protein intended for use in cell culture, differentiation studies and functional assays. |
Size | 400µg |
Concentration | n/a |
Applications | Cell activation, Cell culture studies, B cell growth induction, in vitro cell differentiation studies |
Other Names | CSF-2 |
Gene, Accession, CAS # | n/a |
Catalog # | DDX-C-rhuGM-CSF-4 |
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Order / More Info | Recombinant Human GM-CSF from DENDRITICS SAS |
Product Specific References | n/a |
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