产品详情 |
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Antigenic Specificity | Junction Plakoglobin (JUP) |
Clone | CN-3 |
Host Species | Mouse |
Reactive Species | cow, human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Junction Plakoglobin(JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. |
Immunogen | Recombinant chicken plakoglobin. |
Other Names | arvd12|ctnng|dp3|dpiii|pdgb|pkgb|plak|ARVD12|CTNNG|DP3|DPIII|PDGB|PKGB|D930025P04Rik|PG|jup|cb80|danPG|fb11b06|wu:fb11b06 |
Gene, Accession # | Gene ID: 3728,445543 |
Catalog # | ABIN343605 |
Price | |
Order / More Info | Junction Plakoglobin (JUP) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 7604000, 10837025 |
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