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| Product Name | Bromodomain Containing 1, Recombinant, Human, aa556-680, GST-tag |
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| Description | Purity ~95% (SDS-PAGE). The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. BRD1 is a bromodomain containing protein that has been identified as a susceptibility gene in neurological disorders, such as schizophrenia and bipolar affective disorder. This protein can be used for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. Source: Recombinant protein corresponding to aa556-680 from human Bromodomain |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Bromodomain Containing 1, Recombinant, Human, aa556-680, GST-tag (BRD1, DKFZp686F0325, BR140-like protein, BRL, BRPF1, BRPF2, Bromodomain and PHD finger-containing protein 2) |
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| Gene, Accession, CAS # | BRD1, Gene ID: 23774, Accession: O95696 |
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| Catalog # | 219503 |
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| Order / More Info | Bromodomain Containing 1, Recombinant, Human, aa556-680, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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