| 产品详情 |
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| Product Name | Smo Antagonist, SA1 |
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| Description | MW: 448.53. Purity ≥95% by NMR. Background: A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC?? = 3.1 uM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the beta-galactosidase activity (IC?? = 3.8 uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. |
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| Size | 2 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3-(3-(4-Fluorophenyl)-2,5,7-trimethylpyrazolo[1,5a]pyrimidin-6-yl)-N-(4-(furan-2-yl)butan-2-yl)propanamide] |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS843128 |
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| Price | |
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| Order / More Info | Smo Antagonist, SA1 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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