产品详情 |
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Antigenic Specificity | Mouse IgD |
Clone | n/a |
Host Species | n/a |
Reactive Species | mouse |
Isotype | n/a |
Format | dextran conjugate |
Size | 10 ug |
Concentration | 100 ug/ml |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Crosslinking membrane IgD on B cells with unconjugated anti-IgD antibody induces B cell proliferation at ug/ml concentrations. By contrast, anti-IgD dextran (anti-IgD dex or anti-delta-dex) induce vigorous B cell proliferation at ng/ml concentrations (Brunswick et al., J. Immunol. 140:3364, 1988). Furthermore, in contrast to unconjugated anti-IgD, anti-IgD-dex-activated B cells undergo substantial Ig class switching and differentiation into Ig-secreting cells in the presence of various second signals, including cytokines and Toll-like receptor ligands (Snapper and Mond, J. Immunol. 157:2229, 1996). Thus, Anti-IgD-dex is an efficient and potent polyclonal B cell activator for studying a wide range of B cell functions. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | FinaBio#0001 |
Price | |
Order / More Info | Mouse IgD Antibody from FINA BIOSOLUTIONS LLC |
Product Specific References | n/a |
产品资料 |
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