| 产品详情 |
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| Antigenic Specificity | CENPE |
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| Clone | 1H12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | ICC/IF, IP, ICC, WB, Flow Cyt |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-CENPE [1H12]. |
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| Immunogen | Recombinant human CENP-E |
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| Other Names | CENP E, Centromere autoantigen E, Centromere protein E 312kDa, Centromereprotein E, Centromeric protein E, KIF10, Kinesin family member 10, Kinesinrelated protein |
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| Gene, Accession # | n/a |
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| Catalog # | IQ254 |
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| Price | |
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| Order / More Info | CENPE Antibody from IMMUQUEST LTD. |
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| Product Specific References | CENPE, a novel human centromereassociated protein required for progression from metaphase to anaphase. Yen T.J ( Embo J,May 1991)PMID: 2022189 PIASgamma is required for faithful chromosome segregation in human cells. DA az-MartA nez LA et al. PLoS One. 2006 Dec 20;1:e53 PMID: 17183683 Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function.Schafer-Hales K et al.Mol Cancer Ther. 2007 Apr;6(4):1317-28. ICC/IFPMID: 17431110 Hu CK et al. Midbody assembly and its regulation during cytokinesis. Mol Biol Cell 23:1024-34 (2012).ICC/IFPMID: 22278743 Serio G et al. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc Natl Acad Sci U S A 108:17337-42 (2011).IHC (PFA fixed) ; HumanPMID: 21987812 Kim Y et al. Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E. Cell 142:444-455 (2010).ICC/IF ; HumanPMID: 20691903 Stimpson KM et al. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet 6: (2010).ICC/IF ; HumanPMID: 20711355 Townsend K et al. Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression. J Biol Chem 284:33939-48 (2009).ICC/IF ; HumanPMID: 19826003 Cheng TS et al. Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. J Biol Chem 283:2454-64 (2008).ICC/IF ; HumanPMID: 18055457 Chang P et al. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol 7:1133-9 (2005)PMID: 16244666 |
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