| 产品详情 |
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| Product Name | Acinus |
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| Description | Purified 60-70%. Peptide (DTSENRPENDVPEPP) corresponding to amino acids 775 to 789 of human AcinusL, 48 to 62 of human AcinusS', or 17 to 31 of human AcinusS, which differ from those of mouse Acinus by one amino acid (2). For use with cat. no. A0600-02. Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Acinus (AAE7, ACN1, AC NON-UTILIZING 1, ACYL-ACTIVATING ENZYME 7, AT3G16910.1, Apoptotic Chromatin condensation inducer in nucleus) (Control Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A0600-02P |
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| Order / More Info | Acinus from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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