产品详情 |
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Product Name | A-61603 |
Description | Purity >98%. The Alpha1 -adrenergic receptors are Gq protein-coupled receptors that play a key role in the modulation of sympathetic nervous system activity and are the site of action for therapeutic agents, such as antihypertensive drugs. A-61603 is a selective Alpha1A -adrenergic receptor agonist that is at least 35-fold more potent at Alpha1A receptor sites than at Alpha1B or Alpha1D . Activation of the Alpha1A -adrenergic receptor by A-61603 has been reported to increase the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nM) much more potently than activation by phenylephrine (; EC50 = 2.3 µM). |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-[5-(4,5-dihydro-1H-imidazol-2-yl)-5,6,7,8-tetrahydro-2-hydroxy-1-naphthalenyl]-methanesulfonamide, monohydrobromide |
Gene, Accession, CAS # | CAS: 107756-30-9 |
Catalog # | LS-H6356 |
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Order / More Info | A-61603 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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