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Product Name | A-967079 |
Description | Purity >98%. A-967079 is a TRPA1 antagonist and cell permeable. It has been found to be a potent blocker of TRPA1 channels. It is an oxime analogue and resembles AP18 from a structural perspective, although it has a methyl addition and a chlorine-fluorine substitution. However, compared with AP18 and HC-030031, A-967079 is significantly more potent (100-fold on human and 24-fold on rat TRPA1) and has a much improved pharmacokinetic profile. A-967079 is also more selective, with >1000-fold selectivity over other TRP channels and >150-fold selectivity over 75 other tested proteins. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1170613-55-4 |
Catalog # | LS-H1812 |
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Order / More Info | A-967079 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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