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| Product Name | Recombinant Hepatitis C virus genotype 1b (strain HC-J4) (HCV) Genome polyprotein |
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| Description | 192-358aa; Partial. MW: 20.2kD. Purity >90% as determined by SDS-PAGE. Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducin |
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| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast), 0.2 mg (Yeast), 0.05 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Genome polyprotein; Genome polyprotein; Core protein p21Alternative name(s):Capsid protein C; p21] |
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| Gene, Accession, CAS # | HCV, Accession: O92972.2 |
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| Catalog # | MBS969709 |
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| Order / More Info | Recombinant Hepatitis C virus genotype 1b (strain HC-J4) (HCV) Genome polyprotein from MYBIOSOURCE INC. |
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| Product Specific References | Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzeevariability and stability.Okamoto H., Kojima M., Okada S., Yoshizawa H., Iizuka H., Tanaka T., Muchmore E.E., Peterson D.A., Ito Y., Mishiro S.Virology 190:894-899(1992) Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.Yanagi M., St Claire M., Shapiro M., Emerson S.U., Purcell R.H., Bukh J.Virology 244:161-172(1998) Evidence for the formation of a heptameric ion channel comp |
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