产品详情 |
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Product Name | A 77-01 |
Description | Potent TGF-βRI (ALK-5) inhibitor (IC50 = 34 nM). Inhibits TGF-β transcriptional activation. Inhibits TGF-β-induced proliferation of lung epithelial cells and SMAD phosphorylation. Inhibits TGF-β-induced epithelial-to-mesenchymal transition (EMT). Also inhibitor of p38 MAPK. Likely active metabolite of A 83-01 (Cat. No. 2939). Purity 98%. MW (observed): 286.33 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]quinoline |
Gene, Accession, CAS # | CAS: 607737-87-1 |
Catalog # | 6712/25 |
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Order / More Info | A 77-01 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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