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Antigenic Specificity | Glial Fibrillary Acidic Protein (GFAP) |
Clone | 6F2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GFAP (55 kD) is selectively located in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer'~™s disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood. |
Immunogen | 6F2 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with glial fibrillary acidic protein from human brain. |
Other Names | GFAP|AI836096|cb345|etID36982.3|gfapl|wu:fb34h11|wu:fk42c12|xx:af506734|zgc:110485 |
Gene, Accession # | Gene ID: 2670 |
Catalog # | ABIN335357 |
Price | |
Order / More Info | Glial Fibrillary Acidic Protein (GFAP) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 3669613 |