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| Product Name | Dorsomorphin |
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| Description | MW: 399.5. Purity >97% (HPLC); NMR (Conforms). AMPK inhibitorA selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 M with no activity at GSK3 and Erk1/2 at 10 M2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.Scientific Background: A potent, selective and reversible ATP-compet |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [LYS6K2; 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine] |
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| Gene, Accession, CAS # | CAS: 866405-64-3 |
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| Catalog # | MBS515055 |
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| Order / More Info | Dorsomorphin from MYBIOSOURCE INC. |
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| Product Specific References | 1. TR Fenton et al. Int. J. Biochem. Cell Biol. 2011 43:47 2. S Li et al. Proc. Natl. Acad. Sci. USA 2010 107:3441 |
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