产品名称 Dorsomorphin from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H14654
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameDorsomorphin
DescriptionPurity >98% by NMR, TLC. Dorsomorphin is a potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM). It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro. Dorsomorphin also induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.
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Other Names6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
Gene, Accession, CAS #CAS: 866405-64-3
Catalog #LS-H14654
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Order / More InfoDorsomorphin from LIFESPAN BIOSCIENCES INC.
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