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| Product Name | Human IL-3 receptor Recombinant (CD123) |
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| Description | MW: 43,330 Da. Purity >97%, as determined by SDS-PAGE and HPLC. CD123 is an α subunit of a heterodimer IL-3 receptor, a member of the cytokine receptor superfamily. It is a 70 kDa protein, which binds IL-3 with high specificity but with low affinity. CD123 is encoded by the IL-3a gene, located in the pseudo-autosomal region (PAR) at the ends of the short arms of the X and Y chromosomes, B-lymphoid blasts from acute lymphoblastic leukemia (ALL) have been shown to express functional CD123 and |
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| Size | 0.01 mg, 0.05 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human IL-3R alpha Recombinant (CD123) ; CD123; IL-3Ra; IL3R; IL3RA; IL1R2] |
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| Gene, Accession, CAS # | IL3RA, Gene ID: 3563, Accession: NP_001254642.1 |
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| Catalog # | MBS553344 |
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| Order / More Info | Human IL-3 receptor Recombinant (CD123) from MYBIOSOURCE INC. |
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| Product Specific References | • pellino 2 is critical for toll-like receptor/interleukin-1 receptor (tlr/IL-1R) -mediated post-transcriptional control .J. Biol. Chem., Jul 2012; 287: 25686 - 25695. • role of toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/toll-like receptor signaling, in resistance to acute pseudomonas aeruginosa lung infection .Infect. Immun., Jan 2012; 80: 100 - 109. • IL-1R-associated kinase-1 mediates protein kinase c-induced il-1? production in monocytes .J. Immunol., |
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