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| Product Name | R162 |
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| Description | MW: 264.28. Purity ≥98% by TLC. R162 is a cell-permeable; nontoxic selective inhibitor of Glutamate Dehydrogenase 1 (GDH1); (Ki = 28.6 uM) which is an upregulated enzyme in human cancers. It shows selectivity over other NADPH-dependent enzymes such as 6-phosphogluconate dehydrogenase (6PGD) and Fumarate hydratase (FH). It showes reduced levels of intracellular fumarate levels and Glutathione peroxidase (GPx) activity with increase in mitochondrial ROS levels. Decreases the tumor growth and in |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1-Hydroxy-2- (2-propen-1-yl)-9; 10-anthracenedione] |
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| Gene, Accession, CAS # | CAS: 64302-87-0 |
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| Catalog # | MBS846323 |
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| Order / More Info | R162 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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