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| Product Name | CRADD, 1-199aa, Human,His tag, E Coli |
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| Description | MW: 24.9kDa (219aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recomb |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Caspase and RIP adapter with death domain; RAIDD; CRADD; Caspase and RIP adapter with death domain; Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain; Death adaptor molecule RAIDD; Death domain containing protein CRADD; MGC9163; RIP associated ICH1/CED3 homologous protein with death domain; RIP associated protein with a death domain.] |
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| Gene, Accession, CAS # | CRADD, Gene ID: 8738, Accession: NP_003796 |
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| Catalog # | MBS203244 |
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| Order / More Info | CRADD, 1-199aa, Human,His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Park HH., (2006). J Mol Biol. 357 (2):358-64.; Chou JJ., (1998) Ceil. 94 (2):171-80.; |
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