| 产品详情 |
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| Product Name | Sucrose octasulfate (potassium salt) |
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| Description | Purity >95%. Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 µM) and inhibit its catalytic activity (IC50 = 4.5 µM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by preventing fibroblast growth factor 2 (FGF-2) binding to endothelial cells and also by removing any pre-bound FGF-2 from these cells (IC50 = ~2 µg/ml). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3,4,6-tetrakis(hydrogen sulfate),1,3,4,6-tetra-O-sulfo-Beta-D-fructofuranosyl a-D-glucopyranoside, octapotassium salt, SOS, Sucrosofate potassium |
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| Gene, Accession, CAS # | CAS: 73264-44-5 |
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| Catalog # | LS-H10060 |
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| Price | |
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| Order / More Info | Sucrose octasulfate (potassium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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