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| Product Name | Cathepsin K Inhibitor Screening Kit (Fluorometric) |
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| Description | Cathepsin K (CTSK, EC 3.4.22.38), a lysosomal cysteine protease, is involved in osteoclastic bone remodeling and resorption. In addition, it also degrades collagen, gelatin and elastin. Cathepsin K Inhibitor Screening Kit utilizes the ability of active Cathepsin K to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin K-specific inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin K. |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screen/study/characterize potential inhibitors of Cathepsin K. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2352 |
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| Order / More Info | Cathepsin K Inhibitor Screening Kit (Fluorometric) from CREATIVE BIOMART |
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| Product Specific References | n/a |
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