| 产品详情 |
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| Antigenic Specificity | Complement C8 |
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| Clone | 056B-373 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, Flo, IHC, IHC-Fr, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Complement C8 Antibody (clone 056B-373) LS-C44994. Recognizes complement component 8 (C8), a 151 kD member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides. |
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| Immunogen | Purified human C8. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | LS-C44994 |
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| Price | |
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| Order / More Info | Complement C8 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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