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Product Name | Cortistatin-14 (trifluoroacetate salt) |
Description | An endogenous neuropeptide agonist of SST1-SST5 (IC50s = 0.5-18.2 nM for human receptors expressed in CCL39 cells); [KC1] competitively inhibits hexarelin binding to GHS-R in pituitary membranes (Ki = 0.54 µM); activates the human MrgX2 receptor expressed in HEK293 cells (EC50 = 1.3 µM); completely inhibits TRH, and partially inhibits VIP, stimulation of cAMP production in GH4 cells (0.01-1 µM); dose-dependently impairs memory retention in mice when delivered after foot shock avoidance training (0.05-5 µg, i.c.v.); dose-dependently reduces growth hormone secretion in rats with a reduction of over 80% at all concentrations after 10 minutes (40-320 µg/kg s.c.) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 186901-48-4 193829-96-8 937031-00-0 CCL 39 SST GHSR GH-4 Mrg-X2 |
Gene, Accession, CAS # | n/a |
Catalog # | 25074-1 |
Price | |
Order / More Info | Cortistatin-14 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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