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| Product Name | TIM-3, Recombinant, Human, aa22-200, FLAG-tag |
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| Description | Highly Purified (~90%). The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]. Source: Recombinant protein corresponding to aa22-200 from human TIM-3, fused to FLAG-tag at C-terminal, expressed in a HEK293 cell expression system. Molecular Weight: ~20.8kD, protein runs at a higher MW by SDS-PAGE due to glycosylation Endotoxin: <1EU/ug AA Sequ |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TIM-3, Recombinant, Human, aa22-200, FLAG-tag (T-Cell Immunoglobulin Mucin Receptor 3, T-Cell Membrane Protein 3, TIMD-3, Hepatitis A Virus Cellular Receptor 2, HAVCR-2, KIM-3) |
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| Gene, Accession, CAS # | Accession: NM_032782.4, SwissProt: Q8TDQ0 |
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| Catalog # | 298482 |
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| Order / More Info | TIM-3, Recombinant, Human, aa22-200, FLAG-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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