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| Product Name | Heat Shock Protein 27, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Heat shock proteins are ubiquitous proteins and have been characterized as cytoprotective molecular chaperones. The typical function of a chaperone is to assist a protein to attain its functional conformation to prevent non-functional aggregation of misfolded proteins. The principal HSP families are HSP90, HSP70, HSP60 and the small HSPs including HSP27, ubiquitin, alpha-crystallin, Hsp20 and others. The common functions of small Hsps are chaperone activity, thermotolerance, inhibition of apoptosis, regulation of cell development, and cell differentiation. Hsp27 has a molecular weight of ~27kD, although it has been shown to form large aggregates of up to 800kD in the cytosol. Hsp27 is found in several types of human cells, including tumour cells. Hsp27 interferes with apoptosis through its ability to interact with and inhibit key components of the apoptotic signaling pathway, including the caspase activation complex. Overexpression of heat shock proteins can inc |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Heat Shock Protein 27, Recombinant, Human (Heat Shock Protein beta-1, HspB1, 28kD, Hsp27, Estrogen-regulated 24kD Protein, Heat Shock 27kD Protein, HSP 27, Stress-responsive Protein 27, SRP27, HSPB1, HSP28) |
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| Gene, Accession, CAS # | SwissProt: P04792 |
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| Catalog # | H1830-51M |
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| Order / More Info | Heat Shock Protein 27, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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